Progress Toward Achieving National HIV/AIDS Strategy Goals for Quality of Life Among Persons Aged ≥50 Years with Diagnosed HIV — Medical Monitoring Project, United States, 2017–2023

Ensuring good quality of life (QoL) among persons with diagnosed HIV (PWH) is a priority of the National HIV/AIDS Strategy (NHAS), which established 2025 goals for improving QoL. Goals are monitored through five indicators: self-rated health, unmet needs for mental health services, unemployment, hunger or food insecurity, and unstable housing or homelessness. Among the growing population of PWH aged ≥50 years, progress toward these goals has not been assessed. Data collected during the 2017-2022 cycles of the Medical Monitoring Project, an annual complex sample survey of U.S. adults with diagnosed HIV, assessed progress toward NHAS 2025 QoL goals among PWH aged ≥50 years, overall and by age group. The recent estimated annual percentage change from baseline (2017 or 2018) to 2022 was calculated for each indicator. Among PWH aged ≥50 years, the 2025 goal of 95% PWH with good or better self-rated health is 46.2% higher than the 2022 estimate. The 2025 goals of a 50% reduction in the other indicators range from 26.3% to 56.3% lower than the 2022 estimates. Decreasing hunger or food insecurity by 50% among PWH aged ≥65 was the only goal met by 2022. If recent trends continue, other NHAS QoL 2025 goals are unlikely to be met. Multisectoral strategies to improve access to housing, employment, food, and mental health will be needed to meet NHAS 2025 goals for QoL among older PWH.


Introduction
As advances in HIV treatment have resulted in improved health and longevity (1), a large and growing proportion of U.S. persons with diagnosed HIV (PWH) are now aged ≥50 years (2).PWH are disproportionately affected by adverse social determinants of health, which affect their HIV-related health (3,4).To ensure good quality of life (QoL) among PWH, in 2022 the National HIV/AIDS Strategy (NHAS) set 2025 goals for improving five QoL indicators (5).These include 1) good or better self-rated health,* 2) unmet need for mental health services, † 3) unemployment, § 4) hunger or * Good or better self-rated health was defined as reporting one's general health at the time of interview to be good, very good, or excellent as opposed to poor or fair.† Unmet need for mental health services among those with any need was defined as reporting needing but not receiving services from a mental health professional during the previous 12 months among all persons reporting receiving, or needing but not receiving, services from a mental health professional.§ Unemployment was defined as reporting being out of work at the time of interview, as opposed to being employed for wages, a homemaker, a student, retired, or unable to work.
The MMWR series of publications is published by the Office of Science, U.S. Centers for Disease Control and Prevention (CDC), U.S.

Data Collection
MMP uses a two-stage sample design: 1) 16 states and Puerto Rico were sampled from among all U.S. states, the District of Columbia, and Puerto Rico and 2) simple random samples of adult PWH were selected annually within participating jurisdictions from the National HIV Surveillance System (NHSS) (6).Interview and medical record abstraction data were collected in annual cycles during June 2017-May 2023.Annual response rates were 100% at the state and territory level and ranged from 40% to 46% at the PWH level.MMP was reviewed by CDC, deemed not research, and was conducted consistent with applicable federal law and CDC policy.† †

Statistical Methods
Data were weighted for unequal selection probabilities, adjusted for nonresponse, and poststratified to NHSS population totals.Among 13,475 PWH aged ≥50 years who participated in the 2017-2022 MMP cycles, weighted prevalence estimates and 95% CIs were calculated for each QoL indicator and theoretically related factors, overall and stratified by age (50-64 versus ≥65 years).For each indicator and theoretically related factor, Poisson regression models were used to calculate the recent estimated annual percentage change (EAPC) from baseline (2017 or 2018 cycle, depending on the indicator) to the 2022 cycle.EAPC measures the average percentage change per year over the period for which it is calculated.The percentage difference between the 2025 NHAS goal and the 2022 estimate, expressed as a percentage of the 2022 estimate, was also calculated (i.e., [2025 goal − 2022 estimate] / 2022 estimate).

Unmet Need for Mental Health Services
The 2025 NHAS goal for PWH aged ≥50 years with unmet need for mental health services among those with a need is 9.4%.The observed need in this population was 18.8% (95% CI = 15.4%-22.1%) in 2017 and 21.5% (95% CI = 16.5%-26.5%)in 2022 (Figure 1) (Supplementary Table 1, https://stacks.cdc.gov/view/cdc/160729).The 2025 goal is 56.3% lower than the 2022 estimate.Overall and stratified by age, minimal change in symptoms of major or other depression and symptoms of generalized anxiety disorder among those with a mental health need during 2017-2022 was observed (Table ).

Discussion
Overall, the five QoL indicators among PWH aged ≥50 years changed little during 2017-2022.QoL estimates among PWH aged ≥65 years were more favorable for unemployment, hunger or food insecurity, and unstable housing or homelessness than among those aged 50-64 years.By 2022, the 2025 goal for decreasing hunger or food insecurity was exceeded among PWH aged ≥65 years.However, for all other indicators and age groups, the magnitude of improvement required to meet 2025 goals suggests these QoL goals will not be met if recent trends continue.The NHAS QoL indicators were adopted in late 2022, leaving <2 years to implement changes to reach 2025 goals (5).A federal implementation plan for achieving QoL goals is still being developed (5).
Evidence-based interventions exist to improve adherence to antiretroviral therapy, and thus viral suppression § § ; however, few are tailored to older PWH, who might have specific challenges (e.g., numerous prescribed medications and social isolation).¶ ¶ PWH have poorer physical and mental health than does the overall U.S. population (7).Structuring HIV care delivery for older PWH to encompass comprehensive management of chronic diseases and disabilities, including § § https://www.cdc.gov/hiv/effective-interventions/treat/index.html¶ ¶ https://ryanwhite.hrsa.gov/sites/default/files/ryanwhite/grants/aging-guidenew-elements.pdf(Accessed May 2024).
programs that support living with health challenges,*** might improve self-rated health and decrease unmet need for mental health services (8).Increasing routine mental health screening and integrating HIV and mental health care could decrease unmet need for these services among PWH (9).Improving QoL and addressing social determinants of health requires a multisectoral approach that moves beyond clinical care.Addressing unemployment can include delivery * PWH aged ≥50 years who reported their general health at the time of interview to be good, very good, or excellent as opposed to poor or fair.† PWH aged ≥50 years who reported needing but not receiving services from a mental health professional during the previous 12 months among all PWH aged ≥50 years reporting receiving, or needing but not receiving, services from a mental health professional.§ National HIV/AIDS Strategy 2025 goals for PWH aged ≥50 years are available online.https://files.hiv.gov/s3fs-public/2022-09/NHAS_Federal_Implementation_Plan.pdf¶ Annual data collection cycles began June 1 of the cycle year and ran through May 30 of the following year.Collection of data on good or better self-rated health began in the 2018 cycle.
*** The Chronic Disease Self-Management Program (https://selfmanagementresource.com/programs/small-group/chronic-disease-self-management-small-group/), Positive Self-Management Program (https://selfmanagementresource.com/ programs/small-group/hiv-positive-self-management-small-group/), or the Living Well with a Disability program (https://www.cdc.gov/mmwr/volumes/65/su/su6501a10.htm).* PWH aged ≥50 years who reported being out of work at the time of interview, as opposed to being employed for wages, a homemaker, a student, retired, or unable to work.† PWH aged ≥50 years who reported being hungry and not eating because of lack of money for food during the previous 12 months.§ PWH aged ≥50 years who reported moving in with others because of financial issues, moving more than two times, being evicted, or living on the street, in a shelter, in a single-room-occupancy hotel, or in a car during the previous 12 months.¶ National HIV/AIDS Strategy 2025 goals for PWH aged ≥50 years are available online.https://files.hiv.gov/s3fs-public/2022-09/NHAS_Federal_Implementation_Plan.pdf** Annual data collection cycles began June 1 of the cycle year and ran through May 30 of the following year.Collection of data on unstable housing or homelessness began in the 2018 cycle.

FIGURE 1 .
FIGURE 1. Trends in the weighted percentage of adults aged ≥50 years with diagnosed HIV with good or better self-rated health* (A) and unmet need for mental health services among those with any need for services † (B), compared with National HIV/AIDS Strategy 2025 goals, § overall and stratified by age group -Medical Monitoring Project, United States, 2017-2022 ¶

FIGURE 2 .C
FIGURE 2. Trends in the weighted percentage of adults aged ≥50 years with diagnosed HIV who experienced unemployment* (A), hunger or food insecurity † (B), and unstable housing or homelessness § (C), compared with National HIV/AIDS Strategy 2025 goals, ¶ overall and stratified by age group -Medical Monitoring Project, United States, 2017-2022** Department of Health and Human Services, Atlanta, GA 30329-4027.Suggested citation: [Author names; first three, then et al., if more than six.] [Report title].MMWR Morb Mortal Wkly Rep 2024;73:[inclusive page numbers].food insecurity, ¶ and 5) unstable housing or homelessness.**Indicator goals are designed to increase good or better selfrated health to 95% and decrease all other indicators by 50% from their respective baselines by 2025.Baseline values and 2025 goals are presented in Figures 1 and 2 and in the Table.As persons age, their needs might change because of increasing age-related comorbidities and becoming eligible for Medicare.Thus, age-stratified estimates of QoL, and factors affecting QoL, among older age groups can help guide intervention strategies.QoL indicators are monitored using data from the Medical Monitoring Project (MMP) (6), a CDC-funded HIV surveillance system.This analysis examined recent trends in QoL indicators among PWH aged ≥50 years (overall and stratified by age 50-64 and ≥65 years), assessed whether recent trends are sufficient to meet NHAS 2025 QoL goals, and examined selected theoretically related factors potentially affecting the indicators (hereafter referred to as factors) to help guide intervention efforts to improve QoL among older PWH.¶ Hunger or food insecurity was defined as reporting being hungry and not eating because of lack of money for food during the previous 12 months.

Table 1 ,
https://stacks.cdc.gov/view/cdc/160729).The 2025 goal is 36.2%lower than the 2022 estimate for PWH aged ≥50 years.Change in unmet need for food assistance or food stamps was minimal, as was unmet need for food or meal delivery overall and by age group (Table), (Supplementary Table 2, https:// stacks.cdc.gov/view/cdc/160728).Supplementary Table 1, https://stacks.cdc.gov/view/cdc/160729).The 2025 goal is 40.8% lower than the 2022 estimate.Over time, except during the 2022 cycle, unstable housing or homelessness was lower among those aged ≥65 years than those aged 50-64 years.Overall and stratified by age, there was little change in unmet need for shelter or housing services during 2017-2022 (Table